Huperzine A ntụ ntụ dị elu

NSOGBU AKPO

A na-ewepụta Huperzine A (CAS 102518-79-6) site na osisi ọgwụ ndị China nke genus Huperzia qiancengta na osisi alkaloid nke anụ ahụ, bụ nke nwere ike, mgbanwe na nhọrọ nke ọgbọ nke abụọ nke acetylcholinesterase inhibitor, ọdịdị nke obere odo ma ọ bụ ọcha crystalline ntụ ntụ. soluble na chloroform, soluble na methanol, ethanol, ubé soluble na mmiri, nwere nnukwu abụba soluble, obere ụmụ irighiri ike n'ụzọ dị mfe banye n'ime ọbara-ụbụrụ mgbochi, na-abanye na Central ukwuu n'ime na-ekesa na ụbụrụ frontal, temporal lobe, hippocampus na ndị ọzọ ụbụrụ akụkụ. jikọtara ya na mmụta na ebe nchekwa, na obere dose nke acetylcholinesterase (AchE) nwere mmetụta mgbochi siri ike, nkesa nke synapses mkpochapụ nke acetylcholine (Ach) ọdịnaya mụbara, si otú ahụ na-eme ka neuronal excitability conduction, ike excitatory mmetụta nke mmụta na ebe nchekwa nke. mpaghara ụbụrụ, iji kwalite ọrụ ọgụgụ isi, welie njide ebe nchekwa ma kwalite ebe nchekwa maka mmeputakwa Jiri. Ọ bụ ọgwụgwọ kacha aga nke ọma maka ọrịa Alzheimer (ọrịa Alzheimer) na China.

Huperzine A 1% ntụ ntụ, aha ya bụ HupA, Huperzina A, Huperzine, Huperzine-A, Selagine, Sélagine. Isi nkọwapụta Hancuikang wetara bụ 1%, 5%, 98%. nke nwere agba aja aja na agba ọcha maka nhọrọ gị. Ọ nwere mmetụta ọgwụ ike dị ike, yabụ biko jiri ya na nlekọta ahụike.

Anyị Huperzine A maka ọrịre bụ ihe niile emechara ọkara, yana dabara adaba maka ụlọ ọrụ nri ruru eru, ụlọ ọrụ nri ahụike, ụlọ ọrụ ihe ọṅụṅụ, ụlọ ọrụ ịchọ mma, ndị ahịa, ụlọ akwụkwọ, ụlọ ọrụ nyocha na ụlọ ọrụ ndị ọzọ ma ọ bụ ụlọ ọrụ nkesa metụtara ya. A naghị atụ aro oriri ozugbo.

Huperzia Serrata na-ebupụta ntụ ntụ  

Ihe nchịkọta Huperzine bụ otu n'ime isi ngwaahịa nke Hancuikang. A na-ewepụta ya na akụkụ osisi a mịrị amị nke ihe ọkụkụ sitere n'okike dị ọcha Huperztaserrata Trev. Isi ihe na-arụsi ọrụ ike bụ huperzine A, anyị huperzia serrata leaf wepụ nwere ike ịkwalite mgbasa ọbara ma wepụ ọbara stasis, ikpochapụ ọkụ na detoxify, belata ọzịza ma wepụ ihe mgbu, ọnya, gbasasịa mkpọchi, hematuria, ọkụ, ọnya ọnụ na ọbara na stool na ọrịa ndị ọzọ. Huperzia serrata wepụ bụ ihe mgbakwunye akụrụngwa a na-ahụkarị na ngalaba ahụike. 

  T nkọwapụta

 Product nkọwapụta30 Y

Ars Osisi wepụ Ọrụ ebube Huperzine A 

Huperzine A bụ alkaloid osisi sitere n'okike, yana nwekwara ike, reversible na nke ukwuu nhọrọ ọgbọ nke abụọ acetylcholinesterase inhibitor, na-enye ntụ ntụ na-acha ọcha na-acha ọcha, na-adị mfe soluble na chloroform, soluble na methanol na ethanol dị ntakịrị soluble na mmiri na abụba dị ukwuu. soluble. Ụmụ irighiri ihe ndị ahụ pere mpe ma nwee ike ịbanye n'ime ihe mgbochi ụbụrụ ọbara n'ụzọ dị mfe n'ime mpaghara nwere njikọ chiri anya na ebe nchekwa na ọrụ mmụta dịka ihu ihu, lobe temporal, na hippocampus nke ụbụrụ. Ọ nwere ike igbochi acetylcholinesterase (AchE), mee ka ọdịnaya nke acetylcholine (Ach) dịkwuo n'ime oghere synapti, na-eme ka ntụgharị uche nke neuron dịkwuo elu, na-ewusi ike mmụta na ikike ncheta. Ọ bụ ụlọ ọrụ ọgwụ kachasị aga nke ọma maka ọgwụgwọ ọrịa Alzheimer nke emepụtara ugbu a.

Acetylcholinesterase bụ enzyme dị na ụbụrụ na-ahụ maka ịkụda neurotransmitter acetylcholine. Otu molekul nke acetylcholinesterase nwere ike imebi ọrụ nke ihe dị ka molekul 25,000 nke acetylcholine. A na-ejikarị enzyme a eme ihe na ndị ọrụ gas akwara n'ihi na oke acetylcholine na ụbụrụ nwere ike ịkpata ọnwụ site na asphyxiation na muscle ahụ mkpọnwụ.Uperzine A Usoro ule ntụ ntụ 

 Huperzine A Usoro ule ntụ ntụ 

chromatography mmiri na-arụ ọrụ dị elu bụ usoro ama ama maka ịchọpụta ọdịnaya Huperzine A. Nke a bụ ụfọdụ ozi gbasara nchọpụta Huperzine A site na iji HPLC:
1. N'iji usoro nyocha HPLC-UV, Huperzine A kewapụrụ na kọlụm C18 chromatographic, na methanol na mmiri na-eji dị ka usoro mkpanaka. Usoro a na-achọpụta Huperzine A na opekempe 0.058 µg/ml n'okpuru ìhè ultraviolet (UV).
2. Jiri usoro HPLC tụọ ọdịnaya nke Huperzine A na ogologo wavelength nchọpụta nke 300 nm, wee kewaa ihe ndị ọzọ adịghị ọcha. Kọlụm chromatographic a na-eji bụ kọlụm chromatographic C18, usoro mkpanaka bụ methanol na 0.05% phosphoric acid solution (pH 3.5). Usoro a Oke ọnụọgụ bụ 0.5 µg/mL.

Ebe ọ bụ na a na-ere Huperzine A dị ka ihe mgbakwunye nri na mgbakwunye ahụike, ọdịnaya ga-adịgasị iche n'oge usoro mmepụta. Anyị ga-enye Huperzine A ụkpụrụ ọdịnaya dị iche iche, yabụ gbaa mbọ jụọ anyị nke ọma tupu ịzụrụ.Uperzia Serrata wepụta uru 

Huperzia Serrata wepụ uru

1. Cholinesterase inhibitors
Huperzia serrata ntụ ntụ bụ cholinesterase inhibitor, nke nwere ike ịkwalite nnyefe nke choline na nkwonkwo akwara akwara;
2. Na-achịkwa irighiri akwara
Mwepụta nke Melaleuca nwere ike ime ka usoro nhụjuanya nke etiti ahụ dị jụụ, na-achịkwa ihe ndị na-akpata akwara, ma mee ka nkwekọrịta nke neuromuscular sie ike;
3. Nweta ikike mmụta
Ihe nchịkọta Huperzine ntụ ntụ nwere ike ịnọgide na-enwe ebe nchekwa nke ọma, welie ikike nke ụbụrụ ụbụrụ, welie ikike mmụta na ikike ncheta, na huperzia serrata herb extract is also used for myasthenia gravis, senile memory drop and uth Learning disability;

4. Ọrịa Alzheimer
A na-eji Huperzine A ntụ ntụ na-agwọ ọrịa nkwarụ dị nro na nke na-adịghị ala ala, na-akwalite nkwalite ncheta nke ndị ọrịa, na-ewusi ike nke mmụta na ndụ ike, ma melite ọrịa ndị na-adịghị mma;
5. Nsogbu ebe nchekwa
Huperzine dị ọcha nwere ike ịgwọ ọnwụ ebe nchekwa, melite asụsụ onye ọrịa, mgbako na ikike moto, ma melite ogo ndụ onye ọrịa;
6. Myasthenia gravis
A na-eji akwụkwọ ọgwụ Huperzia serrata eme ihe n'ụlọ ọgwụ iji meziwanye ike anụ ahụ na ụda akwara nke ndị ọrịa nwere myasthenia gravis, melite ikike aka nke ndị ọrịa, ma melite mgbasa ozi n'etiti synapses akwara.Huperzia weputara anyi

1. Ọgwụ:
Ihe nchịkọta Huperzine a na-ejikarị eme mbadamba nkume huperzine, huperzine A capsules na ndị ọzọ;

2. Huperzine A na-eji ihe ọkụkụ eme ihe maka nkwụsị ebe nchekwa, nsogbu ncheta, na nkwarụ n'etiti ndị agadi na ndị agadi, iji meziwanye ikike ncheta na omume, na ịgwọ myasthenia gravis.

Ebe T

o Zụrụ Huperizine A ntụ ntụ 

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